PuraMatrix® has been used in many different clinical and research applications for more than fifteen years. Its versatility is demonstrated through the large body of literature that covers its broad applications.


Three-dimensional growth matrix for human embryonic stem cell-derived neuronal cells.
J Tissue Eng Regen Med. 2012 May 18. doi: 10.1002/term.1512. [Epub ahead of print]
Yla-Outinen, L, Joki, T, Varjola, M, Skottman, H, Narkilahti, S
NeuroGroup, Institute of Biomedical Technology, University of Tampere, Tampere, Finland; BioMediTech, Tampere, Finland; The Science Center of Pirkanmaa Hospital District, Tampere University Hospital, Tampere, Finland.
Copyright © 2012 John Wiley & Sons, Ltd.

Peptide nanofiber scaffold for brain tissue reconstruction.
Methods Enzymol. 2012;508:177-90.
Leung GK, Wang YC, Wu W.
Li Ka Shing Faculty of Medicine, Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.
Copyright © 2012 Elsevier Inc. All rights reserved.

Engineering neural stem cell fates with hydrogel design for central nervous system regeneration.
Progress in Polymer Science Volume 37, Issue 8, August 2012, Pages 1105–1129. Topical Issue on Biorelated polymers. Available online 12 March 2012.
Liu X, Li X, Katsanevakis E, Zhang N
Clemson-MUSC Bioengineering Program, Department of Bioengineering, Clemson University, Charleston, SC 29425, USA; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA; Department of Orthopedic Surgery, Medical University of South Carolina, Charleston, SC 29425, USA; Institute for Advanced Materials and Nano Biomedicine (iNANO), Tongji University School of Medicine, Shanghai, 200092, China
Copyright © 2012 Elsevier Ltd. All rights reserved.

Cultivation of human neural progenitor cells in a 3-dimensional self-assembling peptide hydrogel.
J Vis Exp. 2012 Jan 11;(59):e3830. doi: 10.3791/3830.
Liedmann A, Rolfs A, Frech MJ.
Albrecht-Kossel-Institute for Neuroregeneration, University of Rostock.
Copyright © 2012 Journal of Visualized Experiments

Peripferal Nerve Regeneration in Response to Synthesized Nanofiber Scaffold Hydrogel.
Life Science Journal, 2012;9(1)
Meng H, Chen R, Xu L, Li W, Chen L, Zhao X.
Pathology Department, First-affiliated Hospital of Zhengzhou University. Institute for NanoBiomedical Technology and Membrane Biology, West China Hospital, Sichuan University, Science Park No 1, Ke Yuan 4th St, Gao Peng Road, Hi-tech Industrial Development Zone, Chengdu, 610041, Sichuan, China

A hybrid nanofiber matrix to control the survival and maturation of brain neurons.
Biomaterials. 2012 Jan;33(2):545-55. Epub 2011 Oct 20.
Sur S, Pashuck ET, Guler MO, Ito M, Stupp SI, Launey T.
Laboratory for Memory and Learning, RIKEN Brain Science Institute, Wako-shi, 351-0198 Saitama, Japan.
Copyright © 2011 Elsevier Ltd. All rights reserved.

Fabrication of micropatterned hydrogels for neural culture systems using dynamic mask projection photolithography.
J Vis Exp. 2011 Feb 11;(48). pii: 2636. doi: 10.3791/2636.
Curley JL, Jennings SR, Moore MJ.
Biomedical Engineering, Tulane University, USA.

Effect of 3D-scaffold formation on differentiation and survival in human neural progenitor cells.
Biomed Eng Online. 2010 Nov 11;9(1):70. [Epub ahead of print]
Ortinau S, Schmich J, Block S, Liedmann A, Jonas L, Weiss DG, Helm CA, Rolfs A, Frech MJ.
Albrecht-Kossel-Institute for Neuroregeneration, University of Rostock, Gehlsheimerstrasse 20, 18147 Rostock, Germany; Institute for Physics, Ernst-Moritz-Arndt University Greifswald, Felix-Hausdorff-Str. 6, 17489 Greifswald, Germany; Electron Microscopic Centre, Institute of Pathology, University of Rostock, Strempelstrasse 14, 18055 Rostock, Germany; Division of Cell Biology and Biosystems Technology, Institute of Biological Sciences, University of Rostock, Albert-Einstein-Strasse 3, 18051 Rostock, Germany

BD© PuraMatrix® peptide hydrogel seeded with Schwann cells for peripheral nerve regeneration.
Brain Res Bull. 2010 Oct 30;83(5):207-13. Epub 2010 Jul 13.
McGrath AM, Novikova LN, Novikov LN, Wiberg M
Department of Integrative Medical Biology, Umeå University, Sweden.
Copyright © 2010 Elsevier Inc. All rights reserved.

Emerging nanotechnology approaches in tissue engineering for peripheral nerve regeneration.
Nanomedicine. 2011 Feb;7(1):50-9. Epub 2010 Aug 6.
Cunha C, Panseri S, Antonini S.
University of Milan-Bicocca, Rizzoli Orthopaedic Institute, University of Bologna, San Raffaele Scientific Institute
Copyright © 2011 Elsevier Inc. All rights reserved.

Matrigel supports survival and neuronal differentiation of grafted embryonic stem cell-derived neural precursor cells.
J Neurosci Res. 2010 Feb 15;88(3):542-51.
Uemura M, Refaat MM, Shinoyama M, Hayashi H, Hashimoto N, Takahashi J
Department of Biological Repair, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.
Copyright 2009 Wiley-Liss, Inc.

Compatibility of human fetal neural stem cells with hydrogel biomaterials in vitro.
Brain Res. 2008 Jan 2;1187:42-51. Epub 2007 Oct 26.
Thonhoff JR, Lou DI, Jordan PM, Zhao X, Wu P.
Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-0620, USA.

Peptide- and collagen-based hydrogel substrates for in vitro culture of chick cochleae.
Biomaterials. 2008 Mar;29(8):1028-42. Epub 2007 Nov 26.
Spencer NJ, Cotanche DA, Klapperich CM
Laboratory for Cellular and Molecular Hearing Research, Department of Otolaryngology, Children’s Hospital, Boston, MA 02115, USA.

Isolation and Culturing of Glial, Neuronal and Neural Stem Cell Types Encapsulated in Biodegradable Peptide Hydrogel.
Topics in Tissue Engineering, Vol. 4. Eds. N Ashammakhi, R Reis, & F Chiellini © 2008.
Shivachar AC
Department of Pharmaceutical Sciences, College of Pharmacy and health Sciences,
Texas Southern University, 3100 Cleburne Street, Houston, Texas, USA

Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision.
Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5054-9. Epub 2006 Mar 20.
Ellis-Behnke RG, Liang YX, You SW, Tay DK, Zhang S, So KF, Schneider GE.
Department of Brain and Cognitive Science, Massachusetts Institute of Technology, 77 Massachusett Avenue, Cambridge, MA 02139-4307, USA.


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