PuraMatrix® has been used in many different clinical and research applications for more than fifteen years. Its versatility is demonstrated through the large body of literature that covers its broad applications.

Soft Tissue Regeneration

A Hybrid Silk/RADA-Based Fibrous Scaffold with Triple Hierarchy for Ligament Regeneration.
Tissue Eng Part A. 2012 Jul;18(13-14):1399-409. Epub 2012 Apr 23.
Chen K, Sahoo S, He P, Ng KS, Toh SL, Goh JC.
Department of Bioengineering, National University of Singapore , Singapore, Singapore .

Combined use of bFGF and GDF-5 enhances the healing of medial collateral ligament injury.
Biochem Biophys Res Commun. 2010 Nov 12;402(2):329-34. Epub 2010 Oct 19.
Saiga K, Furumatsu T, Yoshida A, Masuda S, Takihira S, Abe N, Ozaki T.
Department of Orthopaedic Surgery, Science of Functional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikatacho, Kitaku, Okayama 700-8558, Japan.
Copyright © 2010 Elsevier Inc. All rights reserved.

Significant type I and type III collagen production from human periodontal ligament fibroblasts in 3D peptide scaffolds without extra growth factors.
PLoS One. 2010 Apr 22;5(4):e10305.
Kumada Y, Zhang S
Center for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

The effect of self-assembling peptide nanofiber scaffolds on mouse embryonic fibroblast implantation and proliferation.
Biomaterials. 2009 Feb;30(6):1156-65. Epub 2008 Dec 6.
Dégano IR, Quintana L, Vilalta M, Horna D, Rubio N, Borrós S, Semino C, Blanco J.
CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain.

Multipotency of clonal cells derived from swine periodontal ligament and differential regulation by fibroblast growth factor and bone morphogenetic protein.
J Periodontal Res. 2009 Apr;44(2):238-47. Epub 2008 Oct 29.
Shirai K, Ishisaki A, Kaku T, Tamura M, Furuichi Y.
Division of Periodontology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa Ishikari-Tobetsu, Hokkaido, Japan.

Effects of extracellular matrix analogues on primary human fibroblast behavior.
Acta Biomater. 2008 Jan;4(1):67-75. Epub 2007 Sep 29.
Serban MA, Liu Y, Prestwich GD.
Department of Medicinal Chemistry, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108-1257, USA.


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